Research

Evidence is most useful when the question comes first.

Felipe's current work spans systematic reviews, pairwise and network meta-analysis, clinical evidence reviews, and earlier laboratory and cohort research at UFMG.

Current manuscripts

Under review

  1. 01Under review

    Septal Myectomy Combined with Mitral Valve Repair vs. Replacement in Hypertrophic Cardiomyopathy: A Systematic Review and Meta-analysis

    Menezes CRB, Saffi M, Vendrusculo C, Figueiredo FC, Viana DC, Machado A, Sampaio GM. 2026.

    Systematic review and meta-analysisPROSPERO CRD420261416319
  2. 02Under review

    Histidine-Tryptophan-Ketoglutarate (HTK/Custodiol) Cardioplegia Versus Blood Cardioplegia for Myocardial Protection in Adult Valve Surgery: A Systematic Review and Meta-Analysis

    Figueiredo FC, Machado A, Marques MEG, Saffi M, Pinheiro LF, Menezes CRB, Sousa L, Sampaio GM. 2026.

    Systematic review and meta-analysisPROSPERO CRD420261416550
  3. 03Under review

    Cerebral Autoregulation-Guided BP Targets in Neurocritical Care

    Figueiredo F, Guio AMS, Lele AV. 2026.

    Clinical evidence review
  4. 04Under review

    Durability, Discontinuation, Rebound Progression, and Rechallenge After MAPK-Pathway Inhibition in Pediatric BRAF V600E-Mutant Low-Grade Glioma

    Figueiredo F, et al. 2026.

    Systematic review and meta-analysis

Methods

Evidence synthesis

01

Systematic reviews

Question formulation, reproducible searches, structured appraisal, risk-of-bias assessment, GRADE, and transparent synthesis.

02

Pairwise meta-analysis

Quantitative synthesis for direct comparisons, with attention to heterogeneity, sensitivity analysis, and clinical interpretation.

03

Network meta-analysis

Comparative synthesis across treatment networks when the evidence structure and assumptions make indirect comparison defensible.

Research experience

UFMG

2024

Research Assistant

Instituto Alfa de Gastroenterologia, UFMG

Supported a prospective microbiome cohort involving liver transplant recipients.

  • Coordinated patient recruitment and informed consent.
  • Processed, catalogued, and archived biospecimens under standardized biobanking protocols.

2022

Research Assistant

Hypertension Laboratory, UFMG

Contributed to preclinical cardiovascular research on blood-pressure regulation using MRGPRD-knockout mouse models.

  • Performed tail-cuff plethysmography and analyzed cardiovascular physiology data.
  • Conducted spectrophotometric assays and vascular-reactivity experiments involving almandine-mediated responses and arterial stiffness.

Abstracts & presentations

Selected

  1. 2026

    Conference abstract

    Remimazolam as a Novel Sedative Agent in Adult Intensive Care Units: A Systematic Review and Network Meta-Analysis

    Figueiredo FC, et al. 71st Brazilian Congress of Anesthesiology.

  2. 2024

    Review presentation

    Snakebite Emergencies: A Review

    Figueiredo FC, et al. III National Congress of Trauma and Emergency Medicine.

  3. 2023

    Case presentation

    Myocardial Bridge in Athletes: A Case Study

    Figueiredo FC, et al. 35th Brazilian Congress and 29th Pan-American Congress of Sports Medicine.

Clinical questions

Areas of interest

Pain & perioperative care

Analgesia, recovery, myocardial protection, and clinically meaningful perioperative outcomes.

Airway management

Evidence that can clarify choices in airway assessment and management.

Critical & neurocritical care

Hemodynamic targets, sedation, and outcomes in the care of critically ill patients.

Burn care

Anesthesia and critical-care questions concerning patients with complex burn injuries.

Collaboration fit

Clear scope. Defensible methods. Consistent execution.

Felipe welcomes conversations about evidence-synthesis projects and clinically grounded research in anesthesiology, perioperative medicine, critical care, and adjacent fields.

Discuss a research question